Which Liver Enzymes Metabolize Mitragynine


Mitragynine is a compound that is often found in the leaves of the controversial kratom plant. Some researches claim that this compound has properties similar to opioid painkillers. However, there is no concrete evidence that supports this compound. Mitragyna is often acknowledged as kratom by masses. Kratom is a tropical herb that is extracted in Southeast Asia, with Indonesia and Thailand being the biggest exporter.

The shocking fact is that more than 5 million people in the world consume this herb every day in different forms. The only problem with this herb is it has no medical evidence that confirms its veracity to be used as a suitable drug for recreational purposes.

How is kratom consumed?

The most common way to consume kratom is in powder. However, in today’s time, there are many ways to consume this plant. Traditionally, people would boil kratom leaves and chew them, but the modern-day millennials have their way to consume everything. online kratom shops sell this herb in the form of capsules, powder, drink, dessert, etc. People who consume kratom frequently claim it causes soothing effect in the body and can treat depression.

What are the dangers of using kratom?

There are many side effects of using kratom. Some of which are:

  • Itching
  • Dry mouth
  • Constipation
  • Negative interactions
  • Headache
  • Abdominal pain
  • Loss of appetite
  • Weight loss
  • Addiction

What are the effects of kratom on the liver?

The liver is the most important part of the human body for it is responsible for clearing the body from all kinds of toxins and harmful material. People who consume kratom for a long time are at a higher risk of damaging their liver and kidneys. People who suffer from kidney issues start to experience frequent pain in urination and start having dark-colored urine. That’s not all; yellowing of the skin is also a sign of the damage that kratom causes to the kidneys.

Owing to kratom overdose, the liver stops functioning properly, and kidneys take on the job of clearing the body from all kinds of toxins. When the kidneys overwork, that leads to kidney failure along with liver damage. This, in turn, causes the death of many people. Several studies have proved that there is a strong relationship between kratom intake and kidney damage. This is why doctors suggest people keep away from kratom, but they often despise listening.

How does the liver process kratom?

The basic function of the liver is to remove toxins from the body. However, kratom does nothing but more damage to it. Mitragynine is a compound that is metabolized in the human body with different mechanisms and then gets excreted in the urine. Keep in mind; mitragynine is a very strong alkaloid that cannot be adjusted by the body easily. Liver enzymes are formed when the red blood cells get broken down. However, they are not strong enough to withstand the adverse effects of such compounds in the human body.

Though it is criticized by many, kratom continues to enjoy global popularity.

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